The Pubchem MCP Server MCP server,
connected in one click.
Search PubChem compounds, properties, safety data, bioactivity, and cross-references. Connect the official Pubchem MCP Server MCP server to Claude, ChatGPT, or Cursor through gate — one gateway URL, no config files, security-checked.
Free to start · No credit card · No hosting needed
Add Pubchem MCP Server to your AI in one minute
Pick your client. Copy, paste, done — or let gate handle sign-ins and policies for you.
claude mcp add --transport http pubchem-mcp-server https://pubchem.caseyjhand.com/mcpRun in your terminal, then restart Claude Code.
Pubchem MCP Server · https://pubchem.caseyjhand.com/mcp
What your AI can do with Pubchem MCP Server
Real prompts you can type the moment it's connected — no setup, no docs to read.
“Use “pubchem_search_compounds”: Search PubChem for chemical compounds by identifier (name, SMILES, or InChIKey, batched up to 25), molecular formula in Hill notation, subst.”
“Use “pubchem_get_compound_details”: Get detailed compound information by CID. Returns physicochemical properties (molecular weight, SMILES, InChIKey, XLogP, TPSA, etc.), option.”
“Use “pubchem_get_compound_image”: Fetch a 2D structure diagram (PNG image) for a compound by CID.”
“Use “pubchem_get_compound_3d_structure”: Get a compound's default 3D conformer — atomic coordinates and bonds — for one CID. format="json" (default) returns atoms and bonds parsed i.”
How secure is the Pubchem MCP Server MCP server?
Every server in the gate directory has to pass the same four checks before your AI can touch it. Here's how Pubchem MCP Server holds up.
Security grade A
gate scanned 10 tools on Oct 1, 2026 for prompt injection and risky tool definitions — nothing to flag.
- lowpubchem_search_compounds: Unusually long tool description
- lowpubchem_get_compound_details: Unusually long tool description
Official endpoint
Operated by Pubchem MCP Server (caseyjhand.com) at its documented MCP endpoint — not a third-party mirror or community re-host.
No sign-in needed
This server only exposes public data — no account and no credentials are involved when you connect.
Scanned before it goes live
gate checks every tool for prompt injection, hidden instructions, data-exfiltration hints, and over-broad permissions before the server is available through your gateway.
Watched for drift
If Pubchem MCP Server adds or changes tools later, gate re-scans and alerts you — before your AI acts on the change.
Connected in three steps
Connect your gate
Add one gateway URL to Claude, ChatGPT, or any MCP client. One-time setup, about two minutes.
Pick Pubchem MCP Server
Choose Pubchem MCP Server in the gate directory. No sign-in needed.
Use it anywhere
Pubchem MCP Server's tools are live in every AI client you've connected — with rules and logging built in.
Free to start · No credit card · No hosting needed
The actual tools Pubchem MCP Server exposes
Fetched live from the official endpoint and re-checked daily by gate — not marketing copy.
pubchem_search_compounds — Search PubChem for chemical compounds by identifier (name, SMILES, or InChIKey, batched up to 25), molecular formula in Hill notation, subst
pubchem_get_compound_details — Get detailed compound information by CID. Returns physicochemical properties (molecular weight, SMILES, InChIKey, XLogP, TPSA, etc.), option
pubchem_get_compound_image — Fetch a 2D structure diagram (PNG image) for a compound by CID.
pubchem_get_compound_3d_structure — Get a compound's default 3D conformer — atomic coordinates and bonds — for one CID. format="json" (default) returns atoms and bonds parsed i
pubchem_get_compound_xrefs — Get external database cross-references for a compound: PubMed citations, patent IDs, gene/protein associations, registry numbers, and taxono
pubchem_get_compound_safety — Get GHS (Globally Harmonized System) hazard classification and safety data for one or more compounds by CID. Returns signal word, pictograms
pubchem_get_bioactivity — Get a compound's bioactivity profile: which assays tested it, activity outcomes (Active/Inactive/Inconclusive), target identifiers (NCBI Gen
pubchem_get_compound_interactions — Get a compound's interaction data: drug-drug interactions (DrugBank), drug-food interactions, and chemical-target interactions (binding/acti
+ 2 more tools once connected
Who runs the Pubchem MCP Server MCP server?
The Pubchem MCP Server MCP server at a glance
https://pubchem.caseyjhand.com/mcpQuestions, answered
Is there an official Pubchem MCP Server MCP server?
Yes — Pubchem MCP Server operates its own remote MCP server at pubchem.caseyjhand.com. gate connects you to that official endpoint and adds security scanning, per-tool access rules, and an activity log on top.
How do I connect Pubchem MCP Server to Claude or ChatGPT?
Add gate's gateway URL to your AI client once, then pick Pubchem MCP Server in the directory. No account or sign-in is needed. From then on, Pubchem MCP Server's tools are available in every client you've connected to gate.
Do I need to host anything?
No. Pubchem MCP Server runs the server, and gate is fully managed. You just connect one URL — there's nothing to install, deploy, or maintain.
Is the Pubchem MCP Server MCP server safe to connect?
It's the vendor's official endpoint, and gate scans its tools for prompt injection and hidden instructions before it goes live, re-checks it whenever it changes, and lets you allow, block, or require approval for every single tool.
Is it free?
Yes — you can get started with gate for free and connect Pubchem MCP Server in minutes. No credit card required.
Connect more than just Pubchem MCP Server
Every server below works through the same gateway URL — connect once, add tools anytime.
Squarespace DomainsDesignView →Set up Pubchem MCP Server in: Claude · Claude Code · ChatGPT · Cursor · VS Code
Give your AI Pubchem MCP Server — safely.
One URL. All MCPs. Full control. Free to start.
Get started free