The Nullary MCP server,
connected in one click.
Negative results intelligence for drug discovery — query measured failures via MCP. Connect the official Nullary MCP server to Claude, ChatGPT, or Cursor through gate — one gateway URL, no config files, security-checked.
Free to start · No credit card · No hosting needed
What your AI can do with Nullary
Real prompts you can type the moment it's connected — no setup, no docs to read.
“Use “search_inactive_compounds”: Inactive small-molecule compound-target pairs.”
“Use “search_failed_selectivity”: Small molecules that failed selectivity.”
“Use “search_admet_failures”: Small-molecule ADMET failures.”
“Use “search_failed_guides”: Failed/ineffective CRISPR guides.”
How secure is the Nullary MCP server?
Every server in the gate directory has to pass the same four checks before your AI can touch it. Here's how Nullary holds up.
Official endpoint
Operated by Nullary (nullary.ai) at its documented MCP endpoint — not a third-party mirror or community re-host.
No sign-in needed
This server only exposes public data — no account and no credentials are involved when you connect.
Scanned before it goes live
gate checks every tool for prompt injection, hidden instructions, data-exfiltration hints, and over-broad permissions before the server is available through your gateway.
Watched for drift
If Nullary adds or changes tools later, gate re-scans and alerts you — before your AI acts on the change.
Connected in three steps
Connect your gate
Add one gateway URL to Claude, ChatGPT, or any MCP client. One-time setup, about two minutes.
Pick Nullary
Choose Nullary in the gate directory. No sign-in needed.
Use it anywhere
Nullary's tools are live in every AI client you've connected — with rules and logging built in.
Free to start · No credit card · No hosting needed
The actual tools Nullary exposes
Fetched live from the official endpoint and re-checked daily by gate — not marketing copy.
search_inactive_compounds — Inactive small-molecule compound-target pairs.
search_failed_selectivity — Small molecules that failed selectivity.
search_admet_failures — Small-molecule ADMET failures.
search_failed_guides — Failed/ineffective CRISPR guides.
search_failed_essentiality_screens — Non-dependency / failed essentiality screens.
search_ancestry_specific_failures — Ancestry-specific CRISPR failures.
search_developability_failures — Antibody developability failures.
search_failed_clinical_antibodies — Discontinued/terminated clinical antibodies.
+ 27 more tools once connected
The Nullary MCP server at a glance
https://mcp.nullary.ai/mcpQuestions, answered
Is there an official Nullary MCP server?
Yes — Nullary operates its own remote MCP server at mcp.nullary.ai. gate connects you to that official endpoint and adds security scanning, per-tool access rules, and an activity log on top.
How do I connect Nullary to Claude or ChatGPT?
Add gate's gateway URL to your AI client once, then pick Nullary in the directory. No account or sign-in is needed. From then on, Nullary's tools are available in every client you've connected to gate.
Do I need to host anything?
No. Nullary runs the server, and gate is fully managed. You just connect one URL — there's nothing to install, deploy, or maintain.
Is the Nullary MCP server safe to connect?
It's the vendor's official endpoint, and gate scans its tools for prompt injection and hidden instructions before it goes live, re-checks it whenever it changes, and lets you allow, block, or require approval for every single tool.
Is it free?
Yes — you can get started with gate for free and connect Nullary in minutes. No credit card required.
Connect more than just Nullary
Every server below works through the same gateway URL — connect once, add tools anytime.
Squarespace DomainsDesignView →Set up Nullary in: Claude · Claude Code · ChatGPT · Cursor · VS Code